Nucleophilic Vinylic Substitution in Perfluoroacylchromenes. Diastereoselective Synthesis of Push–Pull Enamino Ketones
نویسندگان
چکیده
The reactions of 2-perfluoroacyl-1H-benzo[f]chromenes and 6,7-dimethyl-3-trifluoroacetyl-4H-chromene with primary aliphatic amines ammonia afforded a series enamino ketones containing (2-hydroxynaphthalen-1-yl)methyl or 2-hydroxybenzyl substituent in the ?-position respect to carbonyl group. These involved opening pyran ring, which followed aza-Michael addition as initial step. obtained were found exist DMSO solution single E isomers.
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ژورنال
عنوان ژورنال: Russian Journal of Organic Chemistry
سال: 2021
ISSN: ['1608-3393', '1070-4280']
DOI: https://doi.org/10.1134/s1070428021070046